Cognomen Regina Irene (Regina Irene 
) , in the world, is an extremely rare last name. The last name Regina Irene is habitual in Latin America and the Caribbean, particularly Chile, where it is a very rare surname. More frequently, Regina Irene is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Regina Irene | Ecuador, Philippines, Germany, Chile, Peru |